Savage Worlds - Fallout: A Pale Horse
The ghouls native to New Astoria claim to have been here for hundreds of years, and their claim is hard to dispute. Many of the oldest are pre-War ghouls with memories stretching back to the Old World, and knowledge of the region no one else has, at least not anymore. With the nature of ghoul physiology, it's hard to be sure if those oldest ghouls were Native American at one point or not, and most find it rude to press the question. Regardless, they live now as they believe their ancestors did centuries ago.
The ghouls of New Astoria mostly dwell in the settlement of Clatsop, living life much as the Native Americans of centuries ago did. When human settlers began to move into the area, they found the Clatsop ghouls were helpful enough, especially to those that at least kept their anti-ghoul prejudice in check. They've endured a few attacks over the years, and have fortified Clatsop very well against raider attacks and intrusions. They're happy to share the land and it's bounty with the human settlers, and they have even been known to accept non-feral ghouls from other lands into their "tribe". The ghouls are led by Chief Comcomly, one of the oldest ghouls in the entire region.